May 8, 2025

Medical Coding Osteoporosis

By Janine Mothershed

Medical Coding & Billing for Osteoporosis: Guidelines and Tips

Osteoporosis is a common condition, especially among older adults, characterized by decreased bone density and increased fracture risk. Accurate diagnosis coding and proper billing for osteoporosis and its related complications are essential for ensuring patient care continuity, appropriate reimbursement, and audit protection. This blog highlights key ICD-10-CM codes, CPT codes, and documentation tips to optimize coding and billing for osteoporosis.

ICD-10-CM Diagnosis Coding for Osteoporosis

Osteoporosis coding in ICD-10-CM is classified based on:

  • Cause (age-related, drug-induced, idiopathic, postmenopausal, etc.)

  • Presence of current pathological fracture

Common ICD-10-CM Codes for Osteoporosis:

CodeDescription
M81.0Age-related osteoporosis without current pathological fracture
M81.8Other osteoporosis without current pathological fracture
M82.0–M82.8Osteoporosis in diseases classified elsewhere
M80.0–M80.88Osteoporosis with current pathological fracture (specify site)

Tip: Always check for documentation of fractures. Use M80 codes only if there is a current pathologic fracture.

Example:

  • M80.051A – Age-related osteoporosis with current pathological fracture, right femur, initial encounter

CPT Codes for Osteoporosis-Related Services

Most osteoporosis-related services fall into evaluation, lab, imaging, and treatment categories.

Bone Density Testing (DEXA Scan):

CPT CodeDescription
77080DXA scan, axial skeleton (hip, spine)
77081DXA scan, appendicular skeleton (peripheral)
77085DXA with vertebral fracture assessment
77086Vertebral fracture assessment only

Use ICD-10 code Z13.820 if the test is for screening purposes.

Office Visits:

  • 99202–99215 – Evaluation and management codes (based on time/complexity)

Osteoporosis Treatment Injections (e.g., Prolia, Reclast):

CPT CodeDescription
J0897Injection, denosumab (Prolia), 1 mg
J3489Injection, zoledronic acid (Reclast), 1 mg
96372Therapeutic, prophylactic, or diagnostic injection (subcutaneous or intramuscular)
96365–96379Infusion administration (for IV bisphosphonates)

Documentation Best Practices

  • Specify type of osteoporosis: Age-related, postmenopausal, drug-induced, etc.

  • Indicate presence of fracture: And specify if it’s current, old, or healed.

  • Fracture site and laterality: Ensure it matches ICD-10 laterality requirements.

  • Screening vs Diagnostic: Screening requires Z-codes; diagnostic requires M-codes.

  • Drug-induced osteoporosis: Must document both the drug effect and osteoporosis.

Billing Tips & Compliance

  • Preventive Services: Medicare covers a DEXA scan once every 2 years if criteria are met. Use modifier GY if billing for non-covered services.

  • Link ICD-10 codes carefully: Ensure the diagnosis supports the procedure/test billed.

  • Check frequency limits: Especially for imaging and high-cost injectable medications.

  • Use appropriate encounter designations: E.g., “A” for initial, “D” for subsequent, “S” for sequelae with fracture codes.

Common Coding Errors to Avoid

  • Using M81 when a fracture is present – M80 series should be used if a pathological fracture exists.

  • Failing to document the cause of osteoporosis – Especially needed for M82 and drug-induced cases.

  • Incorrect DEXA coding – Ensure you’re not underbilling by skipping vertebral assessment or using outdated codes.

Risk Adjustment & HCC Coding

Osteoporosis (especially with fracture) impacts HCC (Hierarchical Condition Category) risk scores. Documenting and coding correctly ensures accurate risk adjustment, especially in value-based care models.

  • M80 codes = HCC relevant

  • M81 codes (without fracture) = may not carry HCC weight unless coexisting conditions apply

Accurate osteoporosis coding requires attention to documentation details, especially fracture status, cause, and laterality. Following these coding and billing tips not only supports clinical care but also ensures compliance and optimal reimbursement.

AAPC Orthopedic Coding Alert https://www.aapc.com/codes/coding-newsletters/my-orthopedic-coding-alert/faqs-break-down-pathologic-fracture-coding-for-the-best-dx-169840-article

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