April 28, 2025

Medical Coding Polycystic Ovary Syndrome (PCOS)

By Janine Mothershed

Medical Coding Guidelines & Tips for Coding & Billing Polycystic Ovary Syndrome (PCOS)

Polycystic Ovary Syndrome (PCOS) is a common endocrine disorder affecting millions of women of reproductive age. Because it involves a wide range of symptoms and comorbidities, accurate medical coding and billing are essential to ensure proper reimbursement, reduce claim denials, and maintain compliance.

Below is a comprehensive guide for coding and billing PCOS-related encounters.

Understanding PCOS

PCOS is characterized by a hormonal imbalance that affects ovulation. Common clinical features include:

  • Irregular menstrual cycles

  • Hyperandrogenism (acne, hirsutism)

  • Polycystic ovaries on ultrasound

  • Obesity

  • Insulin resistance

  • Infertility

PCOS is often associated with conditions such as:

  • Type 2 diabetes

  • Metabolic syndrome

  • Cardiovascular disease

  • Depression and anxiety

ICD-10-CM Code for PCOS

E28.2 – Polycystic ovarian syndrome

This is the primary code for documenting PCOS. It should be used when PCOS is diagnosed by clinical evaluation, lab results, and/or imaging.

Common Associated Diagnosis Codes

Since PCOS can present with a variety of symptoms, you may need to code for associated conditions as well:

  • E66.9 – Obesity, unspecified

  • E11.9 – Type 2 diabetes mellitus without complications

  • N92.5 – Other specified irregular menstruation

  • L68.0 – Hirsutism

  • L70.0 – Acne vulgaris

  • F32.9 – Major depressive disorder, single episode, unspecified

  • F41.9 – Anxiety disorder, unspecified

  • N97.9 – Female infertility, unspecified

Always ensure that each diagnosis is supported by clinical documentation in the medical record.

CPT/HCPCS Codes for PCOS Management

While there isn’t a specific CPT code for PCOS itself, management and treatment may involve several services:

Evaluation and Management (E/M) Codes

  • 99202–99215 – Office or outpatient visits (based on time or medical decision-making)

Diagnostic Testing

  • 76830 – Transvaginal pelvic ultrasound

  • 80061 – Lipid panel

  • 84443 – TSH (thyroid-stimulating hormone)

  • 84153 – Total testosterone

  • 84436 – Estradiol

  • 83036 – Hemoglobin A1c

Treatment Services

  • 96372 – Therapeutic, prophylactic, or diagnostic injection

  • J1050 – Medroxyprogesterone acetate (Depo-Provera), per 1 mg

  • S9480 – Intensive outpatient psychiatric services, per diem (if treating mental health)

Tip: Always verify payer-specific policies for diagnostic tests and procedures related to PCOS.

Billing and Documentation Tips

  • Use the Most Specific Code: Always choose the most accurate diagnosis code based on documentation. Avoid unspecified codes when more specific options exist.

  • Link Diagnoses with Services: Make sure all tests and procedures are clearly linked to the appropriate diagnosis on the claim form.

  • Support with Documentation: Ensure the medical record includes:

    • Chief complaint and symptoms

    • Relevant history and physical exam findings

    • Lab/imaging results

    • Assessment and treatment plan

  • Include Comorbid Conditions: These can affect medical decision-making and justify higher E/M levels.

  • Check for Prior Authorization: Some insurance plans require prior approval for imaging (e.g., pelvic ultrasound) or endocrinology consults.

  • Consider Preventive Services: If addressing long-term risks (e.g., diabetes screening), include appropriate screening codes like Z13.1 (screening for diabetes).

Common Pitfalls to Avoid

  • Undercoding: Not capturing all relevant diagnoses, such as associated obesity or mental health conditions.

  • Overcoding: Reporting services not documented or not medically necessary.

  • Inconsistent Documentation: Discrepancies between provider notes and codes submitted can trigger audits.

  • Missing Z Codes: Forgetting to add contextual codes like Z31.41 (encounter for fertility testing) when relevant.

Medical Coding Bundling and Upcoding https://codingclarified.com/medical-coding-bundling-and-upcoding-guidelines/

PCOS is a multifaceted condition that demands a nuanced approach to coding and billing. By using accurate ICD-10 and CPT codes and ensuring complete documentation, healthcare providers and billing teams can streamline reimbursement, reduce denials, and support better patient care.

https://pmc.ncbi.nlm.nih.gov/articles/PMC7518708/#:~:text=PCOS%20refers%20to%20polycystic%20ovary,0.

Share This