October 13, 2025

Medical Coding Non-Chemo IV Drug & Hydration Coding

By Janine Mothershed

Non-Chemo IV Drug & Hydration Coding — Step-by-Step

First, confirm documentation

  • Route, drug/substance, start & stop times for each infusion, and each push given.

  • IV access site(s) used (one site vs. two distinct sites).

  • Clinical reason for hydration (not just KVO).

Pick the initial code using the hierarchy (per encounter, per IV site)

Hierarchy (highest → lowest):
Therapeutic infusion (96365)Injection/IV push (96374)Hydration (96360).
(Infusion services outrank injections, which outrank hydration.)

Multiple “initials”?

  • Yes, if separate IV sites are medically necessary. You may bill a second initial for the second site (append payer-required modifier like -59/XE to the second initial).

Decide infusion vs. IV push (the 15-minute rule)

  • If the drug ran ≤ 15 minutes, code as IV push (96374/96375/96376).

  • Infusion codes require > 15 minutes; hydration initial requires ≥ 31 minutes.

Time rules & add-ons

  • 96365 (therapeutic infusion, initial) = up to 1 hr (must be ≥ 16 min).

  • +96366 = each additional hour when time is > 30 min beyond a full hour (e.g., 1:31–2:30 = one unit).

  • 96360 (hydration initial) = 31–60 min; +96361 = each additional hour > 30 min beyond the hour.

Sequential vs. concurrent vs. overlapping hydration

Sequential (one after another, same access):

  • New substance/drug after the initial infusion: +96367 (up to 1 hr) and +96366 for extra time if >30 min beyond the hour.

  • New IV push after the initial push/infusion: +96375 (new substance); +96376 for repeat push of the same drug in a facility ≥ 30 min after the prior push.

Concurrent (two infusions running at the same time through the same access):

  • Report +96368 once per encounter (not time-based).

  • Not for hydration (hydration has no concurrent code).

  • Mixing multiple drugs in one bag counts as one infusion, not concurrent.

Overlapping hydration:

  • Do not bill hydration time that overlaps with any other reportable infusion/administration on the same IV access (not separately payable).

  • Hydration before or after other services may be billed if medically necessary and time thresholds are met.

Hydration “gotchas”

  • Must be medically necessary (e.g., dehydration, nephro-protection), not KVO.

  • Minimum 31 minutes to report 96360.

Common code set (non-chemo)

  • 96365 Initial IV infusion, therapy/prophylaxis/diagnosis, up to 1 hr → add +96366 per additional hr (>30 min).

  • +96367 Additional sequential infusion (new substance), up to 1 hr.

  • +96368 Concurrent infusion (once per encounter).

  • 96374 IV push, single/initial substance; +96375 each additional new substance by IV push; +96376 repeat push of the same drug in facility setting (≥30 min later).

  • 96360 Initial hydration, 31–60 min; +96361 each additional hr (>30 min)

Mini decision pathway

  1. List each IV site used. If >1 site, you may have >1 initial (one per site).

  2. For each site, pick the initial by hierarchy (Therapeutic infusion → IV push → Hydration).

  3. For each service, apply time thresholds (infusion >15 min; hydration ≥31 min; add-ons >30 min beyond the hour).

  4. Add sequential (+96367/+96366; +96375/+96376) or concurrent (+96368 once) as applicable. No concurrent hydration.

Worked examples

Two IV sites, both medically necessary

  • Site A: Zosyn infusion 1 hr 20 min → 96365 (initial) + no 96366 (not >30 min beyond 1st hr).

  • Site B: Morphine IV push once → 96374 (second initial on different IV site; append -59/XE per payer).

Hydration before & after a drug infusion (no overlap)

  • Hydration pre 40 min → 96360.

  • Ceftriaxone infusion 1 hr 35 min → 96365 + +96366 (extra time >30 min).

  • Hydration post 50 min → +96361.
    (Do not bill any hydration time that overlaps with the ceftriaxone infusion.)

Concurrent infusions

  • Vancomycin runs 1 hr (initial), Piperacillin-tazobactam overlaps for 45 min through the same line96365 + +96368 once (concurrent is not time-based; only once per encounter).

“Short” infusion

  • Ketorolac runs 14 min → code as IV push 96374 (≤15 min → push).

Repeat push of the same drug

  • Metoclopramide IV push at 10:00 and again at 10:40 in the ED → 96374 (initial) + +96376 (repeat push of same drug in facility, ≥30 min later).

Quick pitfalls to avoid

  • Counting overlapping hydration time with any other infusion (not allowed).

  • Using concurrent codes per hour (they’re once per encounter).

  • Calling multiple drugs in one bag “concurrent” (it’s one infusion, not concurrent).

  • Missing start/stop times—you can’t support add-on hours without them.

Keep at hand (code families)

  • Infusion (non-chemo): 96365, +96366, +96367, +96368.

  • Push (non-chemo): 96374, +96375, +96376.

  • Hydration: 96360, +96361.

If you want, I can turn this into a one-page printable PDF flowchart for your team.

Centers for Medicare & Medicaid Services

AAPC

NAMAS

Download the PDF in the Coding Clarified Medical Coding groups on Facebook: Medical Coding “Clarified” & Medical Coding for Newbies

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