March 10, 2022

Medical Coding ICD10 Changes in 2022

By Janine Mothershed

There are many changes this year when it comes to Medical Coding. It is very important to study the new ICD10 changes to become familiar and comfortable with coding them. Stay on top of the changes. In 2022. This year 159 new codes were added, 25 codes were removed and 27 codes were altered. There are now a total of 72,748 codes to pick from. Here are some of the codes that have changed.


  • J12.82 Pneumonia due to coronavirus disease 2019 (MCC)
  • M35.81 Multisystem inflammatory syndrome (CC)
  • M35.89 Other specified system involvement of connective tissue (CC)
  • Z11.52 Encounter for screening for COVID-19
  • Z20.822 Contact with and (suspected) exposure to COVID-19
  • Z86.16 Personal history of COVID-19
  • U09.9 Sequela related to COVID-19

Post COVID-19

U09.9 Post Covid-19 condition, unspecified or list it to a specific other code if it is due to post Covid

Diseases of the Musculoskeletal System and Connective Tissue

In chapter 13, 25 new codes were added. “Sicca syndrome” was changed to “Sjögren syndrome” and the codes were expanded. Sjögren syndrome with central nervous system involvement is now classified as a CC.

  • M35.07Sjögren syndrome CC

There were seven new codes to describe involvement such as inflammatory arthritis, peripheral nervous system, central nervous system, gastrointestinal, glomerular disease, vasculitis and dental involvement

  • M35.05-M35.0C Dental involvement

Nine codes were added to cover non-radiographic axial:

  • M45.A1-M45.AB Spondyloarthritis by site
  • M54.50 Expansion of low back pain into codes unspecified and M54.41 vertebrogenic low back pain

Three new codes in this chapter will be classified as MCCs:

  • M31.10 Thrombotic microangiopathy, unspecified (MCC)
  • M31.11 Hematopoietic stem cell transplantation-associated thrombotic microangiopathy (MCC)
  • M31.19 Other thrombotic microangiopathy (MCC)

Digestive System

The digestive system includes the addition of 13 new codes within Chapter 11. This includes 10 codes for reporting of gastric intestinal metaplasia:

  • K31.A0 Gastric intestinal metaplasia, unspecified
  • K31.A11 Gastric intestinal metaplasia without dysplasia, involving the antrum
  • K31.A12 Gastric intestinal metaplasia without dysplasia, involving the body (corpus)
  • K31.A13 Gastric intestinal metaplasia without dysplasia, involving the fundus
  • K31.A14 Gastric intestinal metaplasia without dysplasia, involving the cardia
  • K31.A15 Gastric intestinal metaplasia without dysplasia, involving multiple sites
  • K31.A19 Gastric intestinal metaplasia without dysplasia, unspecified site
  • K31.A21 Gastric intestinal metaplasia with low grade dysplasia
  • K31.A22 Gastric intestinal metaplasia with high grade dysplasia
  • K31.A29 Gastric intestinal metaplasia with dysplasia, unspecified

Symptoms, Signs and Abnormal Clinical Laboratory Findings

  • R63.30, R63.31, R63.32, and R63.39 Feeding difficulties
  • R35.81 Nocturnal polyuria
  • R45.88 nonsuicidal self-harm
  • R79.83 Abnormal findings of blood amino-acid level


  • R05.1 Acute Cough- Coughing fit
  • R05.2 Subacute Cough- Insufficiency of cough
  • R05.3 Chronic Cough -Cough that won’t go away
  • R05.4 Cough syncope – Syncope from a cough
  • R05.8 Other specified cough- Various other coughs
  • R05.9 Cough, unspecified- Unidentified cough

Diseases of the Nervous System

Ten codes were added to this chapter, several codes were designated as either CCs or MCCs.

  • G04.82 Acute flaccid myelitis (MCC)
  • G44.86 Cervicogenic headache
  • G92.00 Immune effector cell-associated neurotoxicity syndrome, grade unspecified
  • G92.01 Immune effector cell-associated neurotoxicity syndrome, grade 1
  • G92.02 Immune effector cell-associated neurotoxicity syndrome, grade 2
  • G92.03 Immune effector cell-associated neurotoxicity syndrome, grade 3 (CC)
  • G92.04 Immune effector cell-associated neurotoxicity syndrome, grade 4 (CC)
  • G92.05 Immune effector cell-associated neurotoxicity syndrome, grade 5 (CC)
  • G92.8 Other toxic encephalopathy (MCC)
  • G92.9 Unspecified toxic encephalopathy (MCC) Factors Influencing

Health Status and Contact with Health Services

There are 22 new codes that have been added to Chapter 21.

  • Less than a high school diploma (Z55.5)
  • A lack of drinking water (Z58.6)

These codes have been expanded to further specify homelessness: 

  • Z59.00, Z59.01 and Z59.02 Unspecified, sheltered, and unsheltered
  • Z59.41 Food insecurity is broken down into food insecurity and Z59.48 other specified lack of adequate food

Housing instability codes:

  • Z59.811 Housing instability, housed with risk of homelessness
  • Z59.812 Housing instability, housed, homelessness in past 12 months
  • Z59.819 Housing instability, housed unspecified
  • Z59.89 other problems related to housing and economic circumstances

Additional codes have been added for personal history of suicidal behavior, non-suicidal self-harm, Chimeric Antigen Receptor T-cell therapy, other cellular therapy, and gene therapy.

Conditions Originating in the Perinatal Period

An additional eight codes this year related to abnormal findings in Neonatal screening.

  • P09.1-P09.9 cover abnormal findings of inborn errors of metabolism, congenital endocrine and hematologic disease, cystic fibrosis, critical congenital heart disease, neonatal hearing loss, and codes for other abnormal findings or unspecified findings.
  • P00.82 Newborns affected by positive maternal group B streptococcus (GBS) colonization

CC Designations

Additional codes that will be designated as CCs include:

  • A79.82 Anaplasmosis [A. phagocytophilum]
  • C56.3 Malignant neoplasm of bilateral ovaries
  • C79.63 Secondary malignant neoplasm of bilateral ovaries
  • C84.7A Anaplastic large cell lymphoma, ALK-negative, breast
  • I5A Non-ischemic myocardial injury (non-traumatic)

Injuries, Poisonings and Certain Other Consequences of External Causes

Chapter 19 has the most added codes with 45 being new.

MCCs: S06.A0XA Traumatic brain compression without herniation, initial encounter

S06.A1XA Traumatic brain compression with herniation, initial encounter

T40.711A-T40.716S and T40.721A-T40.726S (39 codes) Adverse effects, underdosing and poisonings due to cannabis and synthetic cannabinoids

These are some of the main updates in 2022. Feel free to check out the links below to learn more. More Facts  AAPC

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